Pain and joint instability lead the symptoms reported at a German EDS clinic
findingevidence: probable
Rauterberg and colleagues found that pain was the complaint most often reported to severely affect daily activities at a German EDS clinic. Their 2025 paper surveyed 99 adults attending University Hospital Cologne, including 80 with hEDS or HSD, 16 with classical EDS, and three with classical-like EDS. Of the 98 who answered the daily-activity question, 59 reported musculoskeletal pain (60.2%), 38 joint instability (38.8%), 36 other orthopedic problems (36.7%), 35 digestive complaints (35.7%), and 32 fatigue (32.7%). Respondents could name more than one complaint. These figures describe one specialist clinic.
Not medical advice. This page summarizes research and does not recommend any course of care.
| EDS types | hEDS, HSD, cEDS, clEDS |
|---|---|
| Date | 2025 |
| Diagnostic criteria | 2017 International Classification |
| Last checked | 2026-09-16 |