Patient experience and diagnostic odyssey
What hEDS/HSD patients actually present with — the 2025 German cohort
establishedfinding
The 2025 German outpatient cohort (n=105, diagnosed 2021–2024) shows the real-world presentation profile: musculoskeletal pain, joint instability and subluxation as dominant features, alongside fatigue and the expected comorbidity load. A current-era complement to the criteria literature.
| Subtype scope | hEDS, HSD |
|---|---|
| Date | 2025 |
| Criteria era | international-2017 |
| Reviewed | 2026-09-16 |