Pain and joint instability lead the symptoms reported at a German EDS clinic

findingevidence: probable

Rauterberg and colleagues found that pain was the complaint most often reported to severely affect daily activities at a German EDS clinic. Their 2025 paper surveyed 99 adults attending University Hospital Cologne, including 80 with hEDS or HSD, 16 with classical EDS, and three with classical-like EDS. Of the 98 who answered the daily-activity question, 59 reported musculoskeletal pain (60.2%), 38 joint instability (38.8%), 36 other orthopedic problems (36.7%), 35 digestive complaints (35.7%), and 32 fatigue (32.7%). Respondents could name more than one complaint. These figures describe one specialist clinic.

Not medical advice. This page summarizes research and does not recommend any course of care.
EDS typeshEDS, HSD, cEDS, clEDS
Date2025
Diagnostic criteria2017 International Classification
Last checked2026-09-16

Evidence