Disease historiography
van Meek'ren reports extraordinary skin extensibility
historical recordevent
Amsterdam surgeon Job Janszoon van Meek'ren documented a 23-year-old patient who could pull the skin of the chest over the head — commonly cited as the first detailed clinical description of the skin phenotype later associated with EDS.
| Subtype scope | unspecified |
|---|---|
| Date | 1682 |
| Criteria era | pre-nosology |
| Reviewed | 2026-09-16 |
Evidence
historicalprimary historical document
Recorded through the historical-review literature; the original report is a 1682 Amsterdam surgical text.