Comorbidities and systemic features
The 2017 criteria formalized multisystem involvement
establishedfinding
The 2017 classification moved EDS from a skin-and-joints frame to an explicitly multisystem one — systemic manifestations entered the hEDS criteria themselves, and companion papers covered GI, cardiovascular-autonomic, pain, and psychiatric comorbidity. This codified what patient communities had long reported.
| Subtype scope | all EDS types |
|---|---|
| Date | 2017-03 |
| Criteria era | international-2017 |
| Reviewed | 2026-09-16 |
Evidence
clinicalconsensus statement